Pub. Date : 2015 May
PMID : 25954124
6 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | EGCG Blocked Phenylephrin-Induced Hypertrophy in H9C2 Cardiomyocytes, by Activating AMPK-Dependent Pathway. | epigallocatechin gallate | protein kinase AMP-activated catalytic subunit alpha 2 | Homo sapiens |
| 2 | Moreover, we showed that AMPK is activated in H9C2 cardiomyocytes by EGCG, and AMPK-dependent pathway participates in the inhibitory effects of EGCG on cardiac hypertrophy. | epigallocatechin gallate | protein kinase AMP-activated catalytic subunit alpha 2 | Homo sapiens |
| 3 | Moreover, we showed that AMPK is activated in H9C2 cardiomyocytes by EGCG, and AMPK-dependent pathway participates in the inhibitory effects of EGCG on cardiac hypertrophy. | epigallocatechin gallate | protein kinase AMP-activated catalytic subunit alpha 2 | Homo sapiens |
| 4 | Moreover, we showed that AMPK is activated in H9C2 cardiomyocytes by EGCG, and AMPK-dependent pathway participates in the inhibitory effects of EGCG on cardiac hypertrophy. | epigallocatechin gallate | protein kinase AMP-activated catalytic subunit alpha 2 | Homo sapiens |
| 5 | Taken together, our findings provide the first evidence that the effect of EGCG against cardiac hypertrophy may be attributed to its activation on AMPK-dependent signaling pathway, suggesting the therapeutic potential of EGCG on the prevention of cardiac remodeling in patients with pressure overload hypertrophy. | epigallocatechin gallate | protein kinase AMP-activated catalytic subunit alpha 2 | Homo sapiens |
| 6 | Taken together, our findings provide the first evidence that the effect of EGCG against cardiac hypertrophy may be attributed to its activation on AMPK-dependent signaling pathway, suggesting the therapeutic potential of EGCG on the prevention of cardiac remodeling in patients with pressure overload hypertrophy. | epigallocatechin gallate | protein kinase AMP-activated catalytic subunit alpha 2 | Homo sapiens |