Pub. Date : 2015
PMID : 25948886
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | BACKGROUND AND AIM: The aim of this study was to determine the actions of caffeic acid phenethyl ester (CAPE) on the changes of endothelin-1 (ET-1) level, tumor necrosis factor- (TNF-) alpha, and oxidative stress parameters such as superoxide dismutase (SOD) activities and malondialdehyde (MDA) levels in experimental sepsis model in rats. | caffeic acid phenethyl ester | tumor necrosis factor | Rattus norvegicus |
| 2 | BACKGROUND AND AIM: The aim of this study was to determine the actions of caffeic acid phenethyl ester (CAPE) on the changes of endothelin-1 (ET-1) level, tumor necrosis factor- (TNF-) alpha, and oxidative stress parameters such as superoxide dismutase (SOD) activities and malondialdehyde (MDA) levels in experimental sepsis model in rats. | caffeic acid phenethyl ester | tumor necrosis factor | Rattus norvegicus |
| 3 | RESULTS: Pretreatment with CAPE decreased ET-1, TNF-alpha, and MDA levels in sepsis induced rats. | caffeic acid phenethyl ester | tumor necrosis factor | Rattus norvegicus |
| 4 | CONCLUSION: Our results demonstrate that CAPE may have a beneficial effect on ET and TNF-alpha levels and oxidative stress parameters induced by sepsis in experimental rat models. | caffeic acid phenethyl ester | tumor necrosis factor | Rattus norvegicus |