Title : EGFR Mutations and Resistance to Irreversible Pyrimidine-Based EGFR Inhibitors.

Pub. Date : 2015 Sep 1

PMID : 25948633






2 Functional Relationships(s)
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1 EXPERIMENTAL DESIGN: We performed an N-ethyl-N-nitrosourea (ENU) mutagenesis screen in EGFR-mutant (sensitizing alone or with concurrent EGFR T790M) Ba/F3 cells and selected drug-resistant clones. Ethylnitrosourea epidermal growth factor receptor Mus musculus
2 EXPERIMENTAL DESIGN: We performed an N-ethyl-N-nitrosourea (ENU) mutagenesis screen in EGFR-mutant (sensitizing alone or with concurrent EGFR T790M) Ba/F3 cells and selected drug-resistant clones. Ethylnitrosourea epidermal growth factor receptor Mus musculus