Title : Effect of triptolide on expression of thrombospondin-1 and transforming growth factor-β1 in renal tubular cells.

Pub. Date : 2015 Jul

PMID : 25945607






2 Functional Relationships(s)
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1 Human renal tubular epithelial cells were stimulated by different concentrations of triptolide (0.1, 1, and 10 mug/L) in the presence of angiotensin-II (10(-7)mol/L). triptolide angiotensinogen Homo sapiens
2 The expression of thrombospondin-1 and transforming growth factor beta1 induced by angiotensin-II were down-regulated markedly with 1 mug/L and 10 mug/L of triptolide in mRNA and protein levels (p < 0.05, p < 0.01). triptolide angiotensinogen Homo sapiens