Title : Sulforaphane prevents doxorubicin-induced oxidative stress and cell death in rat H9c2 cells.

Pub. Date : 2015 Jul

PMID : 25936432






1 Functional Relationships(s)
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1 The results revealed that the pre-treatment of H9c2 rat myoblasts with sulforaphane decreased the apoptotic cell number (as shown by trypan blue exclusion assay) and the expression of pro-apoptotic proteins (Bax, caspase-3 and cytochrome c; as shown by western blot analysis and immunostaining), as well as the doxorubicin-induced increase in mitochondrial membrane potential (measured by JC-1 assay). sulforaphane caspase 3 Rattus norvegicus