Title : Effective incorporation of insulin in mucus permeating self-nanoemulsifying drug delivery systems.

Pub. Date : 2015 Nov

PMID : 25933940






3 Functional Relationships(s)
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1 The development of a novel, mucus permeating SNEDDS formulation for oral insulin delivery containing a hydrophobic ion pair of insulin/dimyristoyl phosphatidylglycerol (INS/DMPG) is presented. dimyristoylphosphatidylglycerol insulin Homo sapiens
2 The incorporation of INS/DMPG in SNEDDS prevented an initial burst release of insulin. dimyristoylphosphatidylglycerol insulin Homo sapiens
3 According to the reported results, the incorporation of the hydrophobic ion pair of INS/DMPG in SNEDDS could be regarded as a promising strategy for the oral delivery of insulin. dimyristoylphosphatidylglycerol insulin Homo sapiens