Pub. Date : 2015 Jun 26
PMID : 25930996
6 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | Fenoterol inhibits LPS-induced AMPK activation and inflammatory cytokine production through beta-arrestin-2 in THP-1 cell line. | Fenoterol | arrestin beta 2 | Homo sapiens |
2 | SiRNA knockdown of beta-arrestin-2 abolished the fenoterol inhibition of LPS-induced AMPK activation and interleukin 1beta (IL-1beta) release, thus beta-arrestin-2 mediated the anti-inflammatory effects of fenoterol on LPS-treated THP-1 cells. | Fenoterol | arrestin beta 2 | Homo sapiens |
3 | SiRNA knockdown of beta-arrestin-2 abolished the fenoterol inhibition of LPS-induced AMPK activation and interleukin 1beta (IL-1beta) release, thus beta-arrestin-2 mediated the anti-inflammatory effects of fenoterol on LPS-treated THP-1 cells. | Fenoterol | arrestin beta 2 | Homo sapiens |
4 | SiRNA knockdown of beta-arrestin-2 abolished the fenoterol inhibition of LPS-induced AMPK activation and interleukin 1beta (IL-1beta) release, thus beta-arrestin-2 mediated the anti-inflammatory effects of fenoterol on LPS-treated THP-1 cells. | Fenoterol | arrestin beta 2 | Homo sapiens |
5 | SiRNA knockdown of beta-arrestin-2 abolished the fenoterol inhibition of LPS-induced AMPK activation and interleukin 1beta (IL-1beta) release, thus beta-arrestin-2 mediated the anti-inflammatory effects of fenoterol on LPS-treated THP-1 cells. | Fenoterol | arrestin beta 2 | Homo sapiens |
6 | These results suggested the beta2-AR agonist fenoterol inhibited LPS-induced AMPK activation and IL-1beta release via beta-arrestin-2 in THP-1 cells. | Fenoterol | arrestin beta 2 | Homo sapiens |