Title : Pharmacological inhibition of caspase-8 limits lung tumour outgrowth.

Pub. Date : 2015 Aug

PMID : 25917370






1 Functional Relationships(s)
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1 Pharmacological inhibition of caspase-8 by z-IETD-FMK robustly reduced tumour outgrowth and this was closely associated with a reduction in the release of pro-inflammatory cytokines, IL-6, TNF-alpha, IL-18, IL-1alpha, IL-33, but not IL-1beta. benzyloxycarbonyl-isoleucyl-glutamyl-threonyl-aspartic acid fluoromethyl ketone interleukin 1 alpha Mus musculus