Title : Astrocyte NMDA receptors' activity sustains neuronal survival through a Cdk5-Nrf2 pathway.

Pub. Date : 2015 Nov

PMID : 25909891






1 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 Active p35/Cdk5 complex in the cytosol phosphorylates Nrf2 at Thr(395), Ser(433) and Thr(439) that is sufficient to promote Nrf2 translocation to the nucleus and induce the expression of antioxidant genes. Serine cyclin dependent kinase 5 Homo sapiens