Title : Interleukin-1β plays a role in the pathogenesis of mesial temporal lobe epilepsy through the PI3K/Akt/mTOR signaling pathway in hippocampal neurons.

Pub. Date : 2015 May 15

PMID : 25903737






1 Functional Relationships(s)
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1 Pre-treatment with inhibitors of the pathway, LY294002 and rapamycin, decreased the expression of p-Akt and p70S6K and alleviated the morphological changes induced by IL-1beta in hippocampal neurons. Sirolimus ribosomal protein S6 kinase B1 Homo sapiens