Title : Induction of endogenous Type I interferon within the central nervous system plays a protective role in experimental autoimmune encephalomyelitis.

Pub. Date : 2015 Jul

PMID : 25869642






1 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 Intrathecal injection of poly I:C to mice showing first symptoms of EAE substantially increased the normal disease-associated expression of IFN-alpha, IFN-beta, interferon regulatory factor-7 and IL-10 in CNS, and disease worsening was prevented for as long as IFN-alpha/beta was expressed. Poly I-C interleukin 10 Mus musculus