Title : Clinical significance of assessing Her2/neu expression in gastric cancer with dual tumor tissue paraffin blocks.

Pub. Date : 2015 Jun

PMID : 25863425






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1 Clinical significance of assessing Her2/neu expression in gastric cancer with dual tumor tissue paraffin blocks. Paraffin erb-b2 receptor tyrosine kinase 2 Homo sapiens
2 Clinical significance of assessing Her2/neu expression in gastric cancer with dual tumor tissue paraffin blocks. Paraffin erb-b2 receptor tyrosine kinase 2 Homo sapiens
3 One paraffin block is routinely used for human epidermal growth factor receptor 2 (Her2/neu) immunohistochemistry (IHC) assessment. Paraffin erb-b2 receptor tyrosine kinase 2 Homo sapiens
4 One paraffin block is routinely used for human epidermal growth factor receptor 2 (Her2/neu) immunohistochemistry (IHC) assessment. Paraffin erb-b2 receptor tyrosine kinase 2 Homo sapiens
5 Here, we investigated if picking 2 paraffin blocks for Her2/neu evaluation on 1 slide is an economical, efficient, and practical method, which may reduce false negativity of Her2/neu IHC assessment due to intratumoral heterogeneity. Paraffin erb-b2 receptor tyrosine kinase 2 Homo sapiens
6 Here, we investigated if picking 2 paraffin blocks for Her2/neu evaluation on 1 slide is an economical, efficient, and practical method, which may reduce false negativity of Her2/neu IHC assessment due to intratumoral heterogeneity. Paraffin erb-b2 receptor tyrosine kinase 2 Homo sapiens
7 Our results implied that using dual paraffin blocks to assess Her2/neu expression of GC may help identify more patients with Her2/neu-positive GC who could benefit from targeted therapy, by reducing false-negative rate of Her2 status assessment. Paraffin erb-b2 receptor tyrosine kinase 2 Homo sapiens
8 Our results implied that using dual paraffin blocks to assess Her2/neu expression of GC may help identify more patients with Her2/neu-positive GC who could benefit from targeted therapy, by reducing false-negative rate of Her2 status assessment. Paraffin erb-b2 receptor tyrosine kinase 2 Homo sapiens
9 Our results implied that using dual paraffin blocks to assess Her2/neu expression of GC may help identify more patients with Her2/neu-positive GC who could benefit from targeted therapy, by reducing false-negative rate of Her2 status assessment. Paraffin erb-b2 receptor tyrosine kinase 2 Homo sapiens