Title : Curcumin Analog L48H37 Prevents Lipopolysaccharide-Induced TLR4 Signaling Pathway Activation and Sepsis via Targeting MD2.

Pub. Date : 2015 Jun

PMID : 25862641






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1 Our previous studies have found that a curcumin analog, L48H37 [1-ethyl-3,5-bis(3,4,5-trimethoxybenzylidene)piperidin-4-one], was able to inhibit LPS-induced inflammation, particularly tumor necrosis factor alpha and interleukin 6 production and gene expression in mouse macrophages. L48H37 interleukin 6 Mus musculus