Title : Combined effect of microRNA, nutraceuticals and drug on pancreatic cancer cell lines.

Pub. Date : 2015 May 25

PMID : 25841339






2 Functional Relationships(s)
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1 RESULTS: miR-101 or miR-24-2 over-expressing cells when treated with lower than IC50 doses of the dietary compounds and drug showed a reduced (37-50%) viability in two cell lines with differential synergistic effect and the outcome for Pro-caspase3, Poly (ADP-ribose) polymerase (PARP) cleavage and PKM2 expression. mir-101 poly(ADP-ribose) polymerase 1 Homo sapiens
2 RESULTS: miR-101 or miR-24-2 over-expressing cells when treated with lower than IC50 doses of the dietary compounds and drug showed a reduced (37-50%) viability in two cell lines with differential synergistic effect and the outcome for Pro-caspase3, Poly (ADP-ribose) polymerase (PARP) cleavage and PKM2 expression. mir-101 poly(ADP-ribose) polymerase 1 Homo sapiens