Pub. Date : 2015
PMID : 25832633
5 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Impact of CYP2C9 polymorphism found in the Chinese population on the metabolism of propofol in vitro. | Propofol | cytochrome P450 family 2 subfamily C member 9 | Homo sapiens |
| 2 | The microsomal CYP2C9 alleles involved in the biotransformation of propofol, a widely used anesthetic agent, were investigated in vitro. | Propofol | cytochrome P450 family 2 subfamily C member 9 | Homo sapiens |
| 3 | To examine the enzymatic activity of the CYP2C9 alleles, kinetic parameters for propofol 4-hydroxylation were determined in recombinant human P450s CYP2C9 microsomes from Sf21 insects cells carrying CYP2C9*1 and other variants. | Propofol | cytochrome P450 family 2 subfamily C member 9 | Homo sapiens |
| 4 | This study is the first to report these rare alleles for propofol metabolism, providing fundamental data for further clinical studies on CYP2C9 alleles for propofol metabolism in vivo. | Propofol | cytochrome P450 family 2 subfamily C member 9 | Homo sapiens |
| 5 | This study is the first to report these rare alleles for propofol metabolism, providing fundamental data for further clinical studies on CYP2C9 alleles for propofol metabolism in vivo. | Propofol | cytochrome P450 family 2 subfamily C member 9 | Homo sapiens |