Title : Fucosterol attenuates lipopolysaccharide-induced acute lung injury in mice.

Pub. Date : 2015 May 15

PMID : 25818525






2 Functional Relationships(s)
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1 Meanwhile, fucosterol inhibited NF-kappaB activation and tumor necrosis factor-alpha, IL-6, and IL-1beta production in LPS-stimulated alveolar macrophages. fucosterol nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105 Mus musculus
2 CONCLUSIONS: In conclusion, the present study demonstrated that fucosterol exhibited a protective effect on LPS-induced acute lung injury, and the possible mechanism is involved in inhibiting NF-kappaB activation, thereby inhibiting LPS-induced inflammatory response. fucosterol nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105 Mus musculus