Title : PGE2-induced IDO1 inhibits the capacity of fully mature DCs to elicit an in vitro antileukemic immune response.

Pub. Date : 2015

PMID : 25815345






1 Functional Relationships(s)
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1 When pulsed with leukemic lysates and matured with PGE2, DCs are impaired in the induction of IFN-gamma secreting CD4(+) and CD8(+) T cells due to IDO1 upregulation. Dinoprostone interferon gamma Homo sapiens