Title : Potentiation of epidermal growth factor-mediated oncogenic transformation by sialidase NEU3 leading to Src activation.

Pub. Date : 2015

PMID : 25803810






2 Functional Relationships(s)
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1 Its up-regulation is also important for promotion of the stage of colorectal carcinogenesis in vivo in human NEU3 transgenic mice treated with azoxymethane for the induction of aberrant crypt foci in the colon mucosa, accompanied by enhanced phosphorylation of EGF receptor (EGFR). Azoxymethane epidermal growth factor receptor Mus musculus
2 Its up-regulation is also important for promotion of the stage of colorectal carcinogenesis in vivo in human NEU3 transgenic mice treated with azoxymethane for the induction of aberrant crypt foci in the colon mucosa, accompanied by enhanced phosphorylation of EGF receptor (EGFR). Azoxymethane epidermal growth factor receptor Mus musculus