Title : Decreased carboxylesterases expression and hydrolytic activity in type 2 diabetic mice through Akt/mTOR/HIF-1α/Stra13 pathway.

Pub. Date : 2015

PMID : 25801056






1 Functional Relationships(s)
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1 The knockdown of HIF-1alpha or DEC1 with shRNA construct abrogated the decrease of the CES1 and CES2 expression induced by the insulin in high glucose condition in HepG2 cells. Glucose carboxylesterase 1 Homo sapiens