Title : Quercetin inhibits the migration and proliferation of astrocytes in wound healing.

Pub. Date : 2015 May 6

PMID : 25793633






2 Functional Relationships(s)
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1 In addition, we found that quercetin significantly decreased the phosphorylation of ERK1/2 and FAK, a downstream ERK signaling protein. Quercetin protein tyrosine kinase 2 Homo sapiens
2 Our findings thus indicate that quercetin inhibits healing in the scratch-wound model of primary astrocytes in two ways: blockade of the G1 to S phase cell cycle transition and inhibition of the ERK/FAK signaling pathway, which may contribute toward decreasing astroglial scar formation in vivo. Quercetin protein tyrosine kinase 2 Homo sapiens