Title : Synergistic anticancer potential of dichloroacetate and estradiol analogue exerting their effect via ROS-JNK-Bcl-2-mediated signalling pathways.

Pub. Date : 2015

PMID : 25791820






2 Functional Relationships(s)
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Protein Name
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1 The occurrence of apoptosis was associated with increased hypo- and hyper-phosphorylation of Bcl-2 Ser(70) and caspase 7 activation. Serine BCL2 apoptosis regulator Homo sapiens
2 Kinase inhibition revealed sustained activation of the JNK pathway caused increased Bcl-2 protein Ser(70) hypo-and hyper-phosphorylation. Serine BCL2 apoptosis regulator Homo sapiens