Pub. Date : 2015 Jun
PMID : 25789687
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Finasteride reduces microvessel density and expression of vascular endothelial growth factor in renal tissue of diabetic rats. | Finasteride | vascular endothelial growth factor A | Rattus norvegicus |
| 2 | When compared with diabetic rats, the glomerular tuft area, glomerular volume, MVD, VEGF protein expression in glomeruli and VEGF mRNA expression in the renal cortex tissue of finasteride-treated rats were significantly decreased (P < 0.05, P < 0.01). | Finasteride | vascular endothelial growth factor A | Rattus norvegicus |
| 3 | CONCLUSIONS: Finasteride reduces the VEGF expression and decreases the MVD in the renal tissue of diabetic rats, suggesting the therapeutic potential of finasteride on diabetic microvascular complications. | Finasteride | vascular endothelial growth factor A | Rattus norvegicus |