Title : Design, Synthesis and Biological Evaluation of Imidazo[1,2-a]pyridine Derivatives as Novel DPP-4 Inhibitors.

Pub. Date : 2015 Oct

PMID : 25787859






1 Functional Relationships(s)
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1 Further, molecular docking revealed that compound 5d could retain key binding features of DPP-4 with the pyridine moiety of imidazo[1,2-a]pyridine ring providing an additional pi-pi interaction with Phe357 of DPP-4. pyridine dipeptidyl peptidase 4 Homo sapiens