Title : Carbamylated low-density lipoprotein attenuates glucose uptake via a nitric oxide-mediated pathway in rat L6 skeletal muscle cells.

Pub. Date : 2015 Jul

PMID : 25779204






3 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 Tyrosine nitration of the insulin receptor substrate-1 (IRS-1) was increased. Tyrosine insulin receptor substrate 1 Rattus norvegicus
2 Tyrosine nitration of the insulin receptor substrate-1 (IRS-1) was increased. Tyrosine insulin receptor substrate 1 Rattus norvegicus
3 Collectively, these findings indicate that cLDL, alone, attenuates glucose uptake via NO-mediated tyrosine nitration of IRS-1 in L6 rat muscle cells and suggests the possibility that cLDL is involved in the pathogenesis of T2DM. Tyrosine insulin receptor substrate 1 Rattus norvegicus