Title : UDP-glucuronosyltransferase (UGT) 1A1 mainly contributes to the glucuronidation of trovafloxacin.

Pub. Date : 2015 Feb

PMID : 25760534






1 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 In human liver microsomes prepared from poor metabolizers (UGT1A1*28/*28), significantly reduced trovafloxacin acyl-glucuronide formation activity was observed, indicating that UGT1A1 mainly, while other UGT members such as UGT1A3 and UGT1A9 partially, contributes to the glucuronidation of trovafloxacin. acyl-glucuronide UDP glucuronosyltransferase family 1 member A9 Homo sapiens