Pub. Date : 1989 Aug
PMID : 2575971
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | In the mice pretreated with PLG, although the striatal DA level was also reduced, mean DA and 5-HT levels were significantly higher than in mice given MPTP alone. | 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine | plasminogen | Mus musculus |
| 2 | It is concluded that PLG can prevent, at least partially, the neurotoxic effect of MPTP. | 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine | plasminogen | Mus musculus |
| 3 | We assume that the mechanism of action of PLG may directly or indirectly reduce MPTP-induced dopaminergic neurotoxicity in the nigrostriatal system or reduce the affinity of MPP+ to melanin in DA cells. | 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine | plasminogen | Mus musculus |