Protein Name plasminogen
Organism Mus musculus
Gene ID 18815
Gene Symbol

Plg

UniProt P20918 (PLMN_MOUSE), Q3V1T9 (Q3V1T9_MOUSE)
Relationships Total Number of functionally related compound(s) : 116
Total Number of Articles : 106
Description

plasminogen

Gene Summary

Enables kinase binding activity. Involved in trans-synaptic signaling by BDNF, modulating synaptic transmission. Acts upstream of or within several processes, including embryonic placenta development; muscle cell cellular homeostasis; and myoblast differentiation. Located in cell surface. Is active in Schaffer collateral - CA1 synapse and glutamatergic synapse. Is expressed in early conceptus; embryo; liver; and secondary oocyte. Human ortholog(s) of this gene implicated in COVID-19; conjunctivitis; hereditary angioedema; plasminogen deficiency type I; and thrombophilia. Orthologous to human PLG (plasminogen). [provided by Alliance of Genome Resources, Jul 2025]

synonyms
  • plasminogen
  • angiostatin
  • plasmin heavy chain A
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Properties