Title : Piezotronic-effect enhanced drug metabolism and sensing on a single ZnO nanowire surface with the presence of human cytochrome P450.

Pub. Date : 2015 Mar 24

PMID : 25758259






1 Functional Relationships(s)
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1 Owing to the unique hydrophobic feature of a ZnO NW that provides a desirable "microenvironment" for the immobilization of biomolecules, our device can effectively stimulate the tolbutamide metabolism by decorating a ZnO NW with cytochrome P4502C9/CYPs reductase (CYP2C9/CPR) microsomes. Tolbutamide cytochrome P450 family 2 subfamily C member 9 Homo sapiens