Pub. Date : 2015 Mar 6
PMID : 25746394
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | NAc Shell Arc/Arg3.1 Protein Mediates Reconsolidation of Morphine CPP by Increased GluR1 Cell Surface Expression: Activation of ERK-Coupled CREB is Required. | Morphine | glutamate ionotropic receptor AMPA type subunit 1 | Rattus norvegicus |
2 | CONCLUSIONS: Arc/Arg3.1 in the NAc shell mediates the reconsolidation of morphine-associated context memory via up-regulating the level of membrane of GluR1, for which the local activation of the ERK-CREB signal pathway, as an upstream mechanism of Arc/Arg3.1, is required. | Morphine | glutamate ionotropic receptor AMPA type subunit 1 | Rattus norvegicus |