Title : Krüppel-like factor 4 is a transcriptional regulator of M1/M2 macrophage polarization in alcoholic liver disease.

Pub. Date : 2015 May

PMID : 25740962






1 Functional Relationships(s)
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1 Chronic alcohol feeding in C57Bl/6 mice led to increased expression of M1 (TNF-alpha, MCP1, and IL-1beta) and M2 (Arg1, Mrc1, and IL-10) genes and the frequency of CD206+CD163+ M2 macrophages in the liver. Alcohols arginase, liver Mus musculus