Title : Simultaneous synthesis and degradation of glutamine in isolated rat liver cells. Effect of vasopressin.

Pub. Date : 1989 Nov 20

PMID : 2573391






1 Functional Relationships(s)
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1 Evidence that such synthesis occurred was obtained by: (i) addition of methionine sulfoximine, an inhibitor of glutamine synthetase, which caused a large increase in the apparent removal of glutamine; and (ii) measurement of the specific radioactivity of L-[1-14C]glutamine which was shown to decrease during incubation. Methionine Sulfoximine glutamate-ammonia ligase Rattus norvegicus