Title : Estrogen receptor alpha mediates epithelial to mesenchymal transition, expression of specific matrix effectors and functional properties of breast cancer cells.

Pub. Date : 2015 Apr

PMID : 25728938






1 Functional Relationships(s)
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1 Notably, loss of ERalpha promoted breast cancer cell migration and invasion by inducing changes in the expression levels of certain matrix macromolecules (especially uPA, tPA, PAI-1) through the EGFR-ERK signaling pathway. Tetradecanoylphorbol Acetate estrogen receptor 1 Homo sapiens