Pub. Date : 2015 Feb 25
PMID : 25716866
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | In the central nucleus of amygdala (CeA), a limbic structure critically involved in the affective dimension of pain, proteins of GluA1 subunits of glutamate AMPA receptors were upregulated during morphine withdrawal, and viral knockdown of CeA GluA1 eliminated the morphine-seeking behavior in withdrawn rats of the pain group. | Morphine | glutamate ionotropic receptor AMPA type subunit 1 | Rattus norvegicus |
| 2 | In the central nucleus of amygdala (CeA), a limbic structure critically involved in the affective dimension of pain, proteins of GluA1 subunits of glutamate AMPA receptors were upregulated during morphine withdrawal, and viral knockdown of CeA GluA1 eliminated the morphine-seeking behavior in withdrawn rats of the pain group. | Morphine | glutamate ionotropic receptor AMPA type subunit 1 | Rattus norvegicus |
| 3 | These results suggest direct MeCp2 repression of GluA1 function as a likely mechanism for morphine-seeking behavior maintained by long-lasting affective pain after morphine withdrawal. | Morphine | glutamate ionotropic receptor AMPA type subunit 1 | Rattus norvegicus |
| 4 | These results suggest direct MeCp2 repression of GluA1 function as a likely mechanism for morphine-seeking behavior maintained by long-lasting affective pain after morphine withdrawal. | Morphine | glutamate ionotropic receptor AMPA type subunit 1 | Rattus norvegicus |