Title : [Current Topics on Vitamin D. The role of active forms of vitamin D in regulation of bone remodeling].

Pub. Date : 2015 Mar

PMID : 25716813






3 Functional Relationships(s)
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1 Meanwhile, the active form of vitamin D3, 1alpha, 25-dihydroxyvitamin D3 [1alpha, 25 (OH) 2D3], upregulates expression of receptor activator of nuclear factor-kappaB ligand (RANKL) in osteoblastic cells. Cholecalciferol tumor necrosis factor (ligand) superfamily, member 11 Mus musculus
2 Meanwhile, the active form of vitamin D3, 1alpha, 25-dihydroxyvitamin D3 [1alpha, 25 (OH) 2D3], upregulates expression of receptor activator of nuclear factor-kappaB ligand (RANKL) in osteoblastic cells. Cholecalciferol tumor necrosis factor (ligand) superfamily, member 11 Mus musculus
3 However, daily administration of an active vitamin D3 analog (eldecalcitol, an osteoporotic therapeutic drug) for a month suppressed RANKL expression in osteoblasts, resulting in suppression of bone resorption. Cholecalciferol tumor necrosis factor (ligand) superfamily, member 11 Mus musculus