Pub. Date : 2015 Apr
PMID : 25712654
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | It is considered a strong constitutive androstane receptor activator, however both CBZ and its main metabolite CBZ 10, 11-epoxide have been reported to be pregnane X receptor (PXR) activators whose maximal efficacy and potency are comparable with the human PXR ligand rifampicin. | Carbamazepine | nuclear receptor subfamily 1 group I member 2 | Homo sapiens |
| 2 | It is considered a strong constitutive androstane receptor activator, however both CBZ and its main metabolite CBZ 10, 11-epoxide have been reported to be pregnane X receptor (PXR) activators whose maximal efficacy and potency are comparable with the human PXR ligand rifampicin. | Carbamazepine | nuclear receptor subfamily 1 group I member 2 | Homo sapiens |
| 3 | It is considered a strong constitutive androstane receptor activator, however both CBZ and its main metabolite CBZ 10, 11-epoxide have been reported to be pregnane X receptor (PXR) activators whose maximal efficacy and potency are comparable with the human PXR ligand rifampicin. | Carbamazepine | nuclear receptor subfamily 1 group I member 2 | Homo sapiens |