Title : Hepatocyte-specific ablation of PP2A catalytic subunit α attenuates liver fibrosis progression via TGF-β1/Smad signaling.

Pub. Date : 2015

PMID : 25710025






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1 These data suggest that hepatocyte-specific ablation of PP2Acalpha protects against CCl4-induced chronic hepatic injury and fibrogenesis and the protective effect is mediated at least partially through the impaired TGF-beta1/Smad signaling. Carbon Tetrachloride transforming growth factor, beta 1 Mus musculus