Title : Regulation of high glucose-mediated mucin expression by matrix metalloproteinase-9 in human airway epithelial cells.

Pub. Date : 2015 Apr 10

PMID : 25704757






2 Functional Relationships(s)
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1 HG activates MMP-9 production, MMP-9 activity and MUC5AC overproduction, which is inhibited by nPG, DMSO and DPI (inhibitors of ROS and NADPH), suggesting that HG-activated mucin synthesis is mediated by NADPH/ROS in 16HBE cells. 3-aminodiphenyleneiodium matrix metallopeptidase 9 Homo sapiens
2 HG activates MMP-9 production, MMP-9 activity and MUC5AC overproduction, which is inhibited by nPG, DMSO and DPI (inhibitors of ROS and NADPH), suggesting that HG-activated mucin synthesis is mediated by NADPH/ROS in 16HBE cells. 3-aminodiphenyleneiodium matrix metallopeptidase 9 Homo sapiens