Pub. Date : 2015 Apr
PMID : 25695959
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | By screening an array of drug uptake transporters in HeLa cells using a recombinant vaccinia-based method, five organic anion-transporting polypeptides (OATP) capable of docetaxel uptake were identified: OATP1A2, OATP1B1, OATP1B3, OATP1C1, and Oatp1b2. | Docetaxel | solute carrier organic anion transporter family member 1B1 | Homo sapiens |
| 2 | An assessment of polymorphisms (SNPs) in SLCO1B1 and SLCO1B3 revealed that a number of OATP1B1 and OATP1B3 variants were associated with impaired docetaxel transport. | Docetaxel | solute carrier organic anion transporter family member 1B1 | Homo sapiens |