Title : Disruption of the cytochrome P-450 1B1 gene exacerbates renal dysfunction and damage associated with angiotensin II-induced hypertension in female mice.

Pub. Date : 2015 May 1

PMID : 25694484






1 Functional Relationships(s)
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1 ANG II also increased renal production of ROS and urinary excretion of thiobarburic acid-reactive substances and reduced the activity of antioxidants and urinary excretion of nitrite/nitrate and the 17beta-estradiol metabolite 2-methoxyestradiol in Cyp1b1(-/-) but not Cyp1b1(+/+) mice. Nitrites angiotensinogen (serpin peptidase inhibitor, clade A, member 8) Mus musculus