Title : A DAP12-dependent signal promotes pro-inflammatory polarization in microglia following nerve injury and exacerbates degeneration of injured neurons.

Pub. Date : 2015 Jun

PMID : 25690660






2 Functional Relationships(s)
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1 Here we demonstrate that DNAX-activating protein of 12 kDa (DAP12), a transmembrane adaptor protein that contains an immunoreceptor tyrosine-based activation motif, is a critical regulator of microglial function after nerve injury. Tyrosine TYRO protein tyrosine kinase binding protein Mus musculus
2 Here we demonstrate that DNAX-activating protein of 12 kDa (DAP12), a transmembrane adaptor protein that contains an immunoreceptor tyrosine-based activation motif, is a critical regulator of microglial function after nerve injury. Tyrosine TYRO protein tyrosine kinase binding protein Mus musculus