Title : Identification of modulators of the nuclear receptor peroxisome proliferator-activated receptor α (PPARα) in a mouse liver gene expression compendium.

Pub. Date : 2015

PMID : 25689681






1 Functional Relationships(s)
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1 In addition to the expected activation of PPARalpha by fibrate drugs, di(2-ethylhexyl) phthalate, and perfluorinated compounds, PPARalpha was activated by benzofuran, galactosamine, and TCDD and suppressed by hepatotoxins acetaminophen, lipopolysaccharide, silicon dioxide nanoparticles, and trovafloxacin. Diethylhexyl Phthalate peroxisome proliferator activated receptor alpha Mus musculus