Pub. Date : 2015 Jun
PMID : 25651822
1 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | Similarly, treatment with YM-58483 after the onset of CIA: (i) reversed the clinical scores; (ii) reduced paw oedema; (iii) attenuated mechanical and thermal hypersensitivity; (iv) improved spontaneous motor activity; (v) decreased periphery production of IL-1beta, IL-6 and TNF-alpha; and (vi) reduced spinal activation of ERK and calmodulin-dependent PKII (CaMKIIalpha). | 4-methyl-4'-(3,5-bis(trifluoromethyl)-1H-pyrazol-1-yl)-1,2,3-thiadiazole-5-carboxanilide | tumor necrosis factor | Mus musculus |