Title : Novel insights into the mechanisms whereby isoflavones protect against fatty liver disease.

Pub. Date : 2015 Jan 28

PMID : 25632182






1 Functional Relationships(s)
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1 In addition, in rodents with alcoholic liver disease or nonalcoholic fatty liver disease/nonalcoholic steatohepatitis, inhibition of AR by isoflavones may improve PPARalpha-mediated fatty acid oxidation, reduce hepatic steatosis, and attenuate CYP2E1-mediated oxidative stress or AR/gut bacterial endotoxin-mediated cytokine overproduction, to alleviate progression of FLD. Isoflavones peroxisome proliferator activated receptor alpha Mus musculus