Pub. Date : 2016 Feb
PMID : 25620490
1 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | By revealing that levels of dihydrodiol dehydrogenase were promptly reduced following Cr(VI) challenge, our data suggested that DDH could be involved in a Cr(VI)-related oxidation to generate massive reactive oxygen species and H2 O2 , and to create intracellular hypoxia, which then increased levels of SUMO-1 activating enzyme subunit 2, and sumoylation of eukaryotic elongation factor-2, to mediate the subsequent molecular and cellular responses, e.g., expression of mesenchymal and stem cell markers. | reactive | aldo-keto reductase family 1 member C1 | Homo sapiens |