Protein Name aldo-keto reductase family 1 member C1
Organism Homo sapiens
Gene ID 1645
Gene Symbol


UniProt Q04828 (AK1C1_HUMAN)
Relationships Total Number of functionally related compound(s) : 261
Total Number of Articles : 178

aldo-keto reductase family 1 member C1

Gene Summary

This gene encodes a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. These enzymes catalyze the conversion of aldehydes and ketones to their corresponding alcohols by utilizing NADH and/or NADPH as cofactors. The enzymes display overlapping but distinct substrate specificity. This enzyme catalyzes the reaction of progesterone to the inactive form 20-alpha-hydroxy-progesterone. This gene shares high sequence identity with three other gene members and is clustered with those three genes at chromosome 10p15-p14. [provided by RefSeq, Jul 2008]

  • aldo-keto reductase family 1 member C1
  • 20 alpha-hydroxysteroid dehydrogenase
  • aldo-keto reductase C
Click to show/hide the synonyms