Title : A systematic review and meta-analysis of the association between OGG1 Ser326Cys polymorphism and cancers.

Pub. Date : 2015 Feb

PMID : 25588927






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1 A systematic review and meta-analysis of the association between OGG1 Ser326Cys polymorphism and cancers. ser326cys 8-oxoguanine DNA glycosylase Homo sapiens
2 This study aims to examine the association between the OGG1 Ser326Cys polymorphism and cancer risk based on meta-analysis. ser326cys 8-oxoguanine DNA glycosylase Homo sapiens
3 Overall, significant association was observed between OGG1 Ser326Cys polymorphism and cancer risk in all genetic models except for heterozygote model (Cys/Cys + Cys/Ser vs Ser/Ser: OR 1.071, 95 % CI 1.019-1.125; Cys/Cys vs Cys/Ser + Ser/Ser: OR 1.159, 95 % CI 1.076-1.248; Cys/Cys vs Ser/Ser: OR 1.202, 95 % CI 1.105-1.308). ser326cys 8-oxoguanine DNA glycosylase Homo sapiens
4 The OGG1 Ser326Cys polymorphism may be a risk factor for cancers of lung, digestive system and head and neck. ser326cys 8-oxoguanine DNA glycosylase Homo sapiens