Pub. Date : 2015 Jun
PMID : 25572867
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | Analysis of cytokines in gastric tissue and serum of ethanol-induced mice showed the levels of tumor necrosis factor-alpha (TNF-alpha) and interleukin-6 (IL-6) were decreased by delta-amyrone in response to NF-kappaB p65. | amyrone | interleukin 6 | Mus musculus |
2 | Analysis of cytokines in gastric tissue and serum of ethanol-induced mice showed the levels of tumor necrosis factor-alpha (TNF-alpha) and interleukin-6 (IL-6) were decreased by delta-amyrone in response to NF-kappaB p65. | amyrone | interleukin 6 | Mus musculus |
3 | These results suggested that delta-amyrone exerts its protective effect on experimental gastric ulcer by inhibiting NF-kappaB signaling pathways, which subsequently reduces overproduction of the inducible enzymes iNOS and suppresses the release of the inflammatory factors TNF-alpha, IL-6 and NO. | amyrone | interleukin 6 | Mus musculus |