Pub. Date : 2015 Mar
PMID : 25562512
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Resveratrol mimics insulin activity in the adipogenic commitment of human bone marrow mesenchymal stromal cells. | Resveratrol | insulin | Homo sapiens |
| 2 | Surprisingly, the analysis of RSV molecular effects demonstrated that the compound completely substitutes insulin, a key component of adipogenic medium. | Resveratrol | insulin | Homo sapiens |
| 3 | We also observed that RSV treatment is associated to enhanced phosphorylation of CREB, a critical effector of insulin adipogenic activity. | Resveratrol | insulin | Homo sapiens |
| 4 | Finally, our observations contribute to the mechanistic elucidation of the well-known RSV positive effect on insulin sensitivity and type 2 diabetes mellitus. | Resveratrol | insulin | Homo sapiens |