Pub. Date : 1989 Sep
PMID : 2556151
8 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Potentiation of the effects of atrial natriuretic factor on the cardiovascular system by amiloride. | Amiloride | natriuretic peptide A | Rattus norvegicus |
| 2 | Amiloride has previously been shown to facilitate receptor binding of atrial natriuretic factor (ANF) to membranes of adrenal cortex and to enhance ANF induced inhibition of steroid secretion in vitro. | Amiloride | natriuretic peptide A | Rattus norvegicus |
| 3 | Amiloride has previously been shown to facilitate receptor binding of atrial natriuretic factor (ANF) to membranes of adrenal cortex and to enhance ANF induced inhibition of steroid secretion in vitro. | Amiloride | natriuretic peptide A | Rattus norvegicus |
| 4 | Amiloride has previously been shown to facilitate receptor binding of atrial natriuretic factor (ANF) to membranes of adrenal cortex and to enhance ANF induced inhibition of steroid secretion in vitro. | Amiloride | natriuretic peptide A | Rattus norvegicus |
| 5 | This interaction of amiloride and ANF also holds true for the cardiovascular system. | Amiloride | natriuretic peptide A | Rattus norvegicus |
| 6 | In spontaneously hypertensive rats ANF-induced decreases in blood pressure were potentiated by amiloride. | Amiloride | natriuretic peptide A | Rattus norvegicus |
| 7 | Binding of labeled ANF to aortic tissue was concentration-dependently increased by amiloride. | Amiloride | natriuretic peptide A | Rattus norvegicus |
| 8 | Therefore it can be suggested that amiloride and ATP interfere with a mechanism regulating the sensitivity of the vascular ANF-receptor for its ligand regarding binding and signal transforming presumably by a kinase mediated phosphorylation/dephosphorylation process. | Amiloride | natriuretic peptide A | Rattus norvegicus |