Pub. Date : 2015 Feb 13
PMID : 25548285
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Coadministration of insulin and FFAs, however, abolished hepatocyte proliferation and triggered CD95-dependent apoptosis due to a JNK-dependent association of the activated EGFR with CD95, subsequent CD95 tyrosine phosphorylation and formation of the death-inducing signaling complex (DISC). | Tyrosine | mitogen-activated protein kinase 8 | Rattus norvegicus |
| 2 | JNK inhibition restored the proliferative insulin effect in presence of FFAs and prevented EGFR/CD95 association, CD95 tyrosine phosphorylation and DISC formation. | Tyrosine | mitogen-activated protein kinase 8 | Rattus norvegicus |